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24-Dec-2019 16:33

Average clearance decreased from 1.3 1/min for 320 to 0.7 1/min for 960 mg FU/m.

Multiple linear regression calculations with dose, body surface area, sex, age, and MTX pretreatment as independent variable and clearance as dependent variable confirmed the dependency of clearance on dose and body surface area but also showed that, with equal FU dose per m, clearance was higher in males than in females, on the average, by 0.22 1/min.

“There is a fundamental lack in our society of female erotic empowerment—knowing what they want,” Harel said. Joy and pleasure can’t get lost in the balance.” There clearly is a demand for their services.

At the same time, she added, there is a lack of male emotional empowerment. Harel and Hirschman outlined their teachings in a 2015 book, Making Love Real: The Intelligent Couple’s Guide to Lasting Intimacy and Connection.

There are “G-spot trauma healers” and “yoni massagers,” and every kind of spiritual sexual healer you can (and can’t) imagine.

Credentials are unreliable, and you have to be careful about whom you trust.

“Once we have a good idea what it is, whether they have attachment wounds, shame, lack of embodiment”—an inability to tune in to their own physical sensations—“negative or incorrect information about sex, etc., then we take them through step-by-step experiences and learning processes to help them experience healing and skill building in these areas.” These exercises, many showcased at the four-hour training, involved voicing uncomfortable feelings, desires, boundaries, and fears in a safe setting.

This included touching clothed bodies erotically or sensually and exploring the emotions and arousal that arises in the process.


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Having already earned a master’s degree in human sexuality, Hirschman was taking classes at the Body Electric School, a sexuality institute known as a leader in erotic education, when she “stumbled upon a pamphlet about the certification in sexological bodywork” at the Institute, she said.

There was also suggestive (although not significant) evidence of a (reducing) influence of age on FU clearance.

“We are in a pretty dramatic shift around sex and relationships,” Celeste Hirschman told the group of nearly 50 people gathered two weeks ago at a spiritual center in Berkeley, California. “These are challenging moments,” Hirschman said, referring to the increasing relevance of her work in recent months as the as the dominant cultural discussion around sex, intimacy, and boundaries has revved up.

“I saw my grandmother and her friends being pretty honest and vulnerable with each other about their marriages and the challenges that they had with other members of their families as well, including their siblings and their adult children.

It felt like it wasn’t a space where everyone had to pretend everything was okay, so that people were actually able to talk about and deal with what is.” For Israeli-born and -raised Harel, “religion was constantly in the background, dictating for me how to live my life,” she said.

“A lot of what I do is helping people realize that they have a choice to live their lives the way they want to.” As a daughter of Holocaust survivors, “one of my responses was to live fully, laugh hard and loud, breath fully, experience emotions, and connect with people deeply and emotionally.

She realized this was becoming an obsession yet she could not help herself.… continue reading »

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